Fluorescent Strontium Phosphate Nanoparticle Plasmid DNA Estrogen Biosensor

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Genetic Tattoo: “Ink” contains gene snippet that modifies the DNA in my forearm cells to light up red as estrogen levels increase.

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Some cool firsts for me today:

• First tattoo
• First genetic modification
• First man (ever!) to inject hormone-monitoring ink

Transdermal Pigmentation Procedure

https://www.loom.com/share/2aa5a6ddd3374b6d896da54d498d3f3e

High Level Overview:

1. Pipette DNA nanoparticle “ink” into tattoo gun

2. Tattoo 1cm lines on forearm until ink runs out

3. Increase pH by 0.3 and tattoo nearby site

4. Repeat 3 times until at 7.6 pH levels

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Tattoo with Markings

Result Under Fluorescence