https://www.youtube.com/watch?v=ifKJurQO7M0

Purpose of This Document

This document analyzes genetic markers associated with ADHD in Marwan Refaat using 23andMe genetic data.

The focus is on the following key pathways:

• Dopaminergic

• Noradrenergic

• Serotonergic

• Other pathways relevant to ADHD.

The goal is to assess ADHD risk factors specific to Marwan’s unique genetic profile. All included data has been tailored for precision and personalized insights.

Genes Associated with ADHD Risk

Dopaminergic Pathway Genes

DRD4 (Dopamine Receptor D4)

Variants like the 7-repeat allele are linked to ADHD.
Affects receptor sensitivity and dopamine signaling in the prefrontal cortex.

Marwan Refaat DRD4 Genes from 23andMe

Table View:

Genes	Marker	Assembly	Position	Variants	Your Genotype
DRD4	rs587776842	Build 37	637537	— or CCGCCGACCTCCT	CCGCCGACCTCCT / CCGCCGACCTCCT
		Build 38	637537	— or CCGCCGACCTCCT	CCGCCGACCTCCT / CCGCCGACCTCCT
DRD4	rs752306	Build 37	637622	C or T	C / C
		Build 38	637622	C or T	C / C
DRD4	rs12720390	Build 37	637932	A or G	G / G
		Build 38	637932	A or G	G / G
DRD4	rs1800443	Build 37	639830	G or T	T / T
		Build 38	639830	G or T	T / T
DRD4	rs762885973	Build 37	640071	— or CGGCCCCGAC	CGGCCCCGAC / CGGCCCCGAC
		Build 38	640071	— or CGGCCCCGAC	CGGCCCCGAC / CGGCCCCGAC
DRD4	rs12720410	Build 37	640254	C or G	C / C
		Build 38	640254	C or G	C / C
DRD4	rs936463	Build 37	640432	C or T	C / C
		Build 38	640432	C or T	C / C
DRD4	rs74991942	Build 37	640502	G or T	T / T
		Build 38	640502	G or T	T / T

DAT1 (SLC6A3 - Dopamine Transporter)

Regulates dopamine reuptake from the synapse.